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00Quantum machine-learning research

QMANN

QMANN studies how classical learning can be combined with quantum memory operations. Its reference path separates Theoretical, Simulation and Hardware modes, with a cost estimate before hardware work. Read each result in the context of its mode and baseline.

Chip fixture beside an unbranded workstation in a conceptual research laboratory
Conceptual hybrid-compute setting · execution modes and cost gate below
Reproducible modes
3
Qubits in simulation
20
Qubits on hardware
4–12
Open licence
Apache-2.0

01Execution modes

Most QML libraries hide the cost surface and the noise model. QMANN exposes both, and ships three explicit modes so you always know what your run actually means.

A simulated result is not a hardware result; the hardware route alone does not establish a general learning advantage.

01

Free

Validate algorithm structure and theoretical bounds before any cost is incurred. Perfect gates, infinite coherence.

Qubits
Unlimited (ideal quantum computer)
Audience
Research papers, theoretical bounds, algorithm design
02

Free (compute only)

Classical simulation with noise modelling and quantum-inspired operations. Ship the science before paying for shots.

Qubits
Up to 20 (with noise modelling)
Audience
Algorithm validation, development, education, reproducible research
03

Paid (estimate before submission)

Run on real quantum devices with cost-estimator gating. Hardware mode requires explicit credentials and a confirmed budget.

Qubits
4–12 (NISQ-bounded)
Audience
Bounded hardware experiments with an approved budget

Theory can shape a question; simulation can test a defined setup. A hardware run needs its own cost, environment and result record before anyone compares it with a classical baseline.

3 modes
20-qubit simulation
Hardware budget gate
Protected chip fixture, unbranded compute module and blank workstation in a dark laboratory
Conceptual hybrid-compute research setting
A hardware run is an evidence decision, not the default execution mode.
  1. 01

    Define the learning question, classical baseline, target metric, and acceptable compute budget.

    Input · question + baseline

  2. 02

    Use theoretical mode to test algorithm structure and expected limits without claiming hardware behaviour.

    Artifact · analytical bounds

  3. 03

    Run the controlled noise model and compare the result with the classical baseline before spending shots.

    Evidence · reproducible run

  4. 04

    Review qubit count, provider route, credentials, estimated shot cost, and the reason hardware is necessary.

    Gate · explicit budget

  5. 05

    Compile accepted hardware work through qmesh and retain the signed run context, result, and limitations.

    Output · provenance record

Model core

Quantum memory layer with entangled qubit registers.

Hybrid controller with parameterised quantum circuits.

Evaluation and use

Advanced error mitigation and measurement strategies.

Healthcare, industrial IoT, autonomous systems modules.

Component map · execution modes and cited techniques remain separate records.

Every technique below maps to a published reference. Pull the paper, read the section, then run the code.

01EPJ Quantum Technology · March 2025

QSegRNN-style segment-based quantum recurrent neural networks. Quantum gates for LSTM operations, hybrid memory cells, enhanced temporal pattern recognition.

02Physical Review · 2025; EPJ Quantum Technology · August 2025

Conditional diffusion-based parameter generation. Classical solution warm-start, adaptive bias correction. Faster convergence with reduced optimisation overhead.

03Cornell Lawler Research · January 2025

Grover-inspired amplitude amplification for optimisation problems. O(√N) speedup for unstructured search with adaptive oracle construction.

04arXiv:2504.00068 · arXiv:2501.15630

Quantum-classical attention integration. Multi-head quantum attention, entanglement-based correlations, configurable quantum attention ratio (0–100%).

05Communications Physics · October 2024

Enhanced virtual distillation with noise resilience. Multiple virtual copies, adaptive thresholds, maintains effectiveness with imperfect gates.

06Recent QEM literature · 2025

ML models for quantum error prediction and correction. Neural network error models, adaptive strategies, real-time error prediction and correction.

These are reference themes to inspect, not evidence of measured QMANN performance.

A1Application and stack annexSector pipelines and qmesh provenance path

Sector — example pipelines

Finance
QAOA portfolio optimisation, fraud detection on transaction streams, market prediction with quantum LSTMs, quantum-enhanced risk modelling and stress testing.
Drug discovery
Quantum transformers for molecular property prediction, drug-target binding affinity, Grover-dynamics molecule generation, ADMET safety prediction.
Materials science
Quantum property prediction, adaptive-VQE crystal structure refinement, battery material design, catalyst design via quantum simulation.
Healthcare
Pattern recognition for diagnosis, optimisation for personalised medicine, protein folding via quantum simulation, clinical-trial patient matching.
Industrial
Quantum anomaly detection for predictive maintenance, classifiers for defect detection, QAOA for logistics, quantum simulation for chemical processes.

When you target hardware, QMANN circuits flow through qmesh for IR lowering, error mitigation, and ed25519-signed run manifests. The same provenance chain that satisfies regulated industries also gives ML researchers fully reproducible benchmarks.

06Quick start

qmann / examplesSH
$ git clone https://github.com/neuraparse/QMANN.git
$ cd QMANN
$ pip install -e .

# 🔬  Theoretical mode (FREE)
$ python examples/01_theoretical_mode.py

# 💻  Simulation mode (FREE)
$ python examples/02_simulation_mode.py

# ⚛️  Hardware mode (PAID — estimate first!)
$ python scripts/estimate_hardware_costs.py --qubits 6 --shots 1000
$ python examples/03_hardware_mode.py

Open research